Liquid- and solid-state 900 MHz NMR spectrometer (USTL)
NMR spectroscopy is a powerful method to probe the atomic-scale structure and dynamics of a wide range of soft matter samples, including polymer materials, nanocomposites, gels, colloids, surfactant self-assemblies, biomacromolecules and liquid crystals. Because NMR gives information on the local atomic scale, it can easily characterize the bonding environment of atoms in soft materials, which often lack long-range positional order. Furthermore, NMR is a sensitive probe of local dynamics at atomic scale over timescales spanning 15 orders of magnitude, from 10-12 s to 102 s. It can thus be used to study motions, including bond vibrations, conformational changes, rotational and translational motions of the molecules.
This high-field (21.1 T) NMR spectrometer is equipped with 4 probes for liquids and 4 probes for solids. High-magnetic field improves the resolution and the sensitivity of NMR spectroscopy. Furthermore, this spectrometer is equipped with a 5 mm 1H/13C/15N/2H cryogenic probe for the study of liquid-state samples. The cryogenic cooling of the probe enhances the sensitivity of liquid-state NMR spectroscopy, and is thus useful for the study of macromolecules. This spectrometer is also equipped with a sample changer (96 positions) for liquid-state NMR samples, which allows the batch screening of a large collections of samples. This instrument is also equipped with 4 probes for the acquisition of NMR spectra of solids under Magic Angle Spinning (MAS) conditions. These probes are suitable for rotors with outer diameters from 7 to 1.3 mm. The 1.3 mm probe permits (i) the acquisition of high-resolution proton spectra in solids and (ii) the detection of low-volume samples. Conversely the 7 mm probe is dedicated to the observation of insensitive isotopes with low gyromagnetic ratio, such as 14N, 17O, 25Mg, and 43Ca. This spectrometer is also equipped with a High-resolution MAS (HR-MAS) probe for the study of soft matter (swollen polymers, membranes, colloidal dispersions).
The specifications of the instrument are listed below:
Field: 21.1 T
Console: Bruker BioSpin Avance Neo 900 MHz 4 channels
Sample changer: SampleJet (96 positions) with temperature at 6, 16°C or room temperature
Temperature: BCU II for variable temperature NMR experiments
Liquid-state NMR probes:
- 5 mm 1H/13C/15N/2H cryogenic probe with z-gradient, temperature range: [-40; 80°C];
- 4 mm 1H/13C/15N/2H HR-MAS probe with z-gradient, temperature range: [2; 50°C];
- 5 mm BBO probe (tuning range: 109Ag-31P) with z-gradient, temperature range: [-150; +180°C];
- 5 mm TXI 1H/13C/15N/2H probe with z-gradient, temperature range: [-150; +150°C].
Solid-state NMR probes:
- 7 mm HX low-γ (143Nd-15N) VTN MAS probe;
- 2.5 mm HX (14N-31P) DVT MAS probe;
- 1.3 mm HX (14N-31P) DVT MAS probe;
- 3.2 mm 1H/13C/15N VTN MAS probe.
Prof. Olivier Lafon
Dr. Julien TREBOSC